Flight BE7212 was surrounded by fire engines when it touched down today "without incident" shortly after 11am.
Emergency services were placed on alert after one of the plane's tyres exploded when it set off from Dusseldorf.
An emergency landing of sorts at Manchester Airport - one of the tyres blew out on take off - very impressive landing from pilot pic.twitter.com/EbYO24lCEt— Seth Bennett (@Sethb45) 18 October 2017
Passengers applauded the pilot on social media after the landing as footage showed the deflated wheel as it came into contact with the runway.
But landed safely at Manchester Airport
Seth Bennett, who was on the flight, tweeted: "An emergency landing of sorts at Manchester Airport - one of the tyres blew out on take off - very impressive landing from pilot – at Manchester Airport."
A Flybe spokesman said: "Flybe can confirm that the above flight landed safely without incident at Manchester Airport this morning having received an indication that one of the tyres located in one of the main landing gear units was deflated.
"On arriving on stand, all 42 passengers disembarked without further incident with no adverse reaction.
"As a precautionary measure, the airport had put its emergency vehicles on standby."
The deflated tyre comes into contact with the runway at Manchester Airport
Flybe said 42 passengers were on board the plane (file image)
Last month, horrifying video footage emerged of the moments after a plane's engine blew apart as it flew over the Atlantic .
In the images posted online by a passenger, a thick cable can be seen flapping in the air after the engine disintegrated and the pilot declared a mayday.
Passengers reacted with horror when the engine of the Air France jet from Paris to the USA failed, forcing the aircraft carrying 520 passengers into an emergency landing.
Travellers described how everything seemed normal until they heard a "loud thud and a lot of vibration".
Air France confirmed there was "serious damage" to one of the plane's four engines before before it landed safely.