Slade, Underhill and McConnochie ruled out of England’s clash with Wales

England’s opening World Cup warm-up Test against Wales has been hit by a trio of withdrawals on the eve of the Twickenham showdown.

Centre Henry Slade, flanker Sam Underhill and wing Ruaridh McConnochie have been ruled out by respective knee, toe and hip injuries.

Slade’s place at 13 goes to Jonathan Joseph, Joe Cokanasiga comes in for McConnochie and Lewis Ludlum plugs the hole in the back row, where Tom Curry switches to openside.