Uncapped duo Lungi Ngidi and Khaya Zondo have been named in South Africa's one-day international squad for the six-match series against India next month.
Seamer Ngidi made his Test bow against India this month, returning figures of 6-39 in the second innings in Pretoria to take seven wickets in the match.
Injury denied Ngidi the chance to make his ODI debut in the previous series against Bangladesh, but he will now have an opportunity to shine in 50-over cricket.
"This is a continuation of vision 2019 as we develop our squad for the 2019 ICC World Cup in England," Cricket South Africa National Selection Panel Convener Linda Zondi said.
"Lungi has achieved a remarkable double in being named Man of the Match on both his T20 and Test match debuts and he now gets the chance to show what he can do in the 50-overs format."
Batsman Zondo was called up for the Proteas' squad for the 2015 tour of India, but did not earn a cap.
"Khaya has been on the fringes of selection for some time now which included leading the South Africa A side on their recent 50-overs campaign against the England Lions," Zondi added.
"He forms part of our vision to give opportunities to fringe players and we will continue this policy throughout the build-up to the World Cup."
South Africa are also boosted by the returns of Morne Morkel and Chris Morris, who were unavailable against Bangladesh due to a side strain and a back injury respectively.
South Africa squad: Faf du Plessis (c), Hashim Amla, Quinton de Kock, AB de Villiers, JP Duminy, Imran Tahir, Aiden Markram, David Miller, Morne Morkel, Chris Morris, Lungisani Ngidi, Andile Phehlukwayo, Kagiso Rabada, Tabraiz Shamsi, Khayelihle Zondo.