Damian Penaud is set to make his international debut on Saturday after France coach Guy Noves rung the changes for the second Test with South Africa in Durban.
A France side missing representatives from Top 14 finalists Clermont Auvergne and Toulon went down 37-14 to the Springboks in Pretoria last weekend.
Skipper Guilhem Guirado is among those to return in a starting XV showing eight alterations, while Clermont centre Penaud - the son of former France fly-half Alain Penaud - will wear the number 13 shirt.
Halves Baptiste Serin and Francois Trinh-Duc, full-back Scott Spedding and forwards Kevin Gourdon, Yoann Maestri and Rabah Slimani are the other players to have been brought in.
South Africa have predictably kept faith with the players who performed so admirably last weekend.
The only change to the Boks side is enforced, with Lionel Mapoe replacing Jesse Kriel, who took a blow to the head in the first Test.
Head coach Allister Coetzee said: "Jan Serfontein had a very good match at inside centre in Pretoria and we wanted a specialist at number 13 as replacement for Jesse, so Mapoe is a logical choice. It also means we're preventing making two changes to the team."