Konrad Hurrell's second try of a dramatic encounter gave the injury-hit Gold Coast Titans a stunning 38-36 victory at leaders Melbourne Storm, while Brisbane Broncos and Penrith Panthers produced storming fightbacks to claim NRL victories.
The Titans only had 14 fit players after losing Jarryd Hayne (leg), Ryan Simpkins (knee) and Dan Sarginson (arm), but triumphed in the face of adversity at Suncorp Stadium on Saturday.
Cooper Cronk scored a first-half brace and Billy Slater also went over as Craig Bellamy's side led 18-16 at half-time, Ryan James, Leivaha Pulu and Anthony Don going over for the Titans.
Hurrell got on the end of a Nathan Peats grubber to put the Titans back in front and Chris McQueen touched down in his 150th appearance, with Kane Elgey converting to put Neil Henry's men 28-18 to the good.
Last year's runners-up came roaring back, though, taking charge with three converted tries in the space of six minutes from Will Chambers, Joe Stimson and Cheyse Blair.
Yet despite seeing State of Origin hopeful Hayne join the injury list, Gold Coast were not finished yet and Tyrone Roberts' converted score cut the gap to two points before Hurrell latched on to Don's tap-back from a cross-field Elgey kick to snatch it.
Brisbane's four-match winning run was in danger of ending in the second game of the day at Suncorp, but they rallied to defeat Manly Sea Eagles 24-14.
Tom Trbojevic, Apisai Koroisau and Jorge Taufua scored tries in the first 10 minutes as Manly lead 14-0 at half-time, but Wayne Bennett's side were transformed following the interval.
Manly lost Trbojevic to an ankle and knee injury and Brisbane added insult to injury, with Corey Oates scoring two tries along with four-pointers from Anthony Milford and Kodi Nikorima which moved the Broncos up to third.
Penrith left themselves with even more to do, overcoming a 28-6 half-time deficit to consign New Zealand Warriors to a 36-28 loss at Pepper Stadium.
Isaah Yeo scored two of six tries for the Panthers, who stopped the rot after five consecutive defeats.