Max Scherzer dominated but the Washington Nationals were unable to stop the Baltimore Orioles extending their winning streak to six in MLB.
Scherzer took a no-hitter into the sixth inning against the Orioles, who rallied for a 5-4 win after 12 innings on Tuesday.
Mark Trumbo's bases-loaded single to left field in the bottom of the 12th inning gave the Orioles a two-game series sweep in Baltimore.
A.J. Griffin starred for the Texas Rangers, and his performance resulted in a win - an 11-0 thrashing of the San Diego Padres.
The Colorado Rockies and Chicago Cubs split their double-header, the latter winning 8-1 after a 10-4 loss.
The Seattle Mariners edged the Philadelphia Phillies 10-9, the Cleveland Indians shut out the Toronto Blue Jays 6-0 and the Cincinnati Reds overcame the New York Yankees 5-3.
The St Louis Cardinals beat the Miami Marlins 6-5, the New York Mets cruised past the San Francisco Giants 6-1 and the Kansas City Royals had a 12-inning, 7-6 win against the Tampa Bay Rays.
The Milwaukee Brewers got past the Boston Red Sox 11-7, the Minnesota Twins beat the Chicago White Sox 7-2 and the Houston Astros claimed an 8-3 win against the Atlanta Braves.
The Detroit Tigers had a 7-3 win against the Arizona Diamondbacks, the Los Angeles Angels beat the Oakland Athletics 7-3 and the Los Angeles Dodgers edged the Pittsburgh Pirates 4-3 after 10 innings.
Rangers right-hander Griffin improved to 4-0 this season with a complete-game shutout of the Padres. Griffin scattered just four hits and struck out four with one walk. He is the first Rangers pitcher to toss a shutout since Colby Lewis on September 11, 2015.
VETERANS IN ACTION
The Astros tagged 43-year-old Bartolo Colon for five runs in the first inning, including a solo home run from 40-year-old Carlos Beltran.
Carlos Beltran (40) homers off Bartolo Colon (43).-- MLB (@MLB) May 10, 2017
Youth wins this round! pic.twitter.com/rrhRyTX4kx
Red Sox pitcher Drew Pomeranz lasted just four innings at Miller Park. He surrendered first-inning home runs to Eric Thames and Keon Broxton as the Brewers jumped out to a 5-1 lead en route to an 11-7 victory. Pomeranz was tagged for six runs on seven hits with just two strikeouts and a pair of walks to Brewers leadoff hitter Jonathan Villar.
ORIOLES AT NATIONALS
Wade Miley (1-1, 2.27 ERA) returns to the mound after getting drilled by a pair of line drives in his last start. The Nationals' (21-12) Stephen Strasburg (3-1, 2.66) will make his third career start against the Orioles (22-10), against whom he has a 2.25 ERA. Both pitchers have been good this season, but each will be tested against dangerous lineups.