Philadelphia Union recorded an overdue win in MLS thanks to C.J. Sapong's quick-fire hat-trick, while Orlando City were routed by Houston Dynamo.
Sapong scored three goals in 11 second-half minutes as the Union defeated New York Red Bulls 3-0 on Saturday.
The American forward's treble helped snap Philadelphia's 15-game regular-season winless streak.
After a goalless first half, Sapong broke the deadlock in the 74th minute, albeit with some help from a deflection, after being denied by a stunning Luis Robles save moments earlier.
Bradley Wright-Phillips thought he had the equaliser not long after but Andre Blake produced a fine diving save to thwart the Red Bulls star.
Sapong then made it 2-0 with a close-range header in the 81st minute before completing his hat-trick from the penalty spot four minutes later.
Houston showed no mercy in a 4-0 demolition of high-flying visitors Orlando.
Mauro Manotas was at the double in the second half to condemn Orlando to back-to-back defeats.
The loss allowed Toronto FC to take spot in the Eastern Conference following their 1-0 win at reigning MLS Cup champions Seattle Sounders.
Jozy Altidore's 23rd-minute penalty settled the contest as Toronto leapfrogged Orlando, who have played a game less.
LA Galaxy overturned a two-goal deficit to salvage a 2-2 draw at home to Chicago Fire, FC Dallas accounted for Real Salt Lake 3-0 and Chris Wondolowski's brace saw San Jose Earthquakes beat Portland Timbers by the same scoreline.
DC United lost 1-0 to Montreal Impact, while Columbus Crew were 2-0 winners against New England Revolution.