Jason Day has been forced to withdraw from next week's WGC-Mexico Championship, citing illness.
World number two Day missed over three months of action last year due to back pain, which also forced him to withdraw from two FedEx Cup playoff events.
He is the only player among the Official World Golf Ranking top 50 expected to miss next week's championship, which is to be held in Mexico City for the first time after previously taking place at Trump National Doral.
"I'm truly disappointed to announce that I won't be able to play in next week's World Golf Championship-Mexico Championship," Day said in a statement.
"I have a double ear infection and the flu, which precludes me from preparing for and playing in the tournament.
"I have heard great things about the Mexico Championship and the golf course. I want to thank the Salinas family for their support of the event. I look forward to teeing it up there next year."