David Warner and Travis Head combined for Australia's highest ODI opening stand, blasting 284 runs to end the Pakistan series on a record-breaking high.
As the Adelaide crowd celebrated Australia Day, they were given plenty to cheer about by Warner (179) and Head (128), who scored the vast bulk of an imposing 369-7.
As well as breaking new ground for their country, the opening pair fell just two runs short of Sanath Jayasuriya and Upul Tharanga's all-time record of 286, set in 2006.
Warner's sixth hundred of the 2016-17 calendar ties an ODI record set by Kumar Sangakkara, while Head's maiden international 50-over century suggests a destructive partnership that could be in place for this year's Champions Trophy.
In response, Pakistan capitulated to 312 all out despite Babar Azam's century, as the hosts wrapped up a 4-1 series win.
But the day belonged to Warner, his explosive improvement in the series seeing him score 58 in the first three games - and 309 in the latter two.
It could have been all so different, however, had Pakistan captain Azhar Ali clung onto a sharp diving catch after Warner had edged Mohammad Amir into the cordon.
The last ODI at the Adelaide Oval had featured a spell of bowling brilliance from Wahab Riaz that had Shane Watson hopping around his crease, but bat comfortably won the battle with ball this time around and once Amir's early swing faded, and the left-armer burned Pakistan's review, Warner and Head dominated.
Warner was already 35 off 25 deliveries when Amir thought he had him caught behind - the 30-year-old responded by belting the hapless Hasan Ali (2-100) for two fours in the next over, as he was consigned to become the 10th bowler in ODI history to concede 100 runs in a match.
Wahab (1-62) and Mohammad Hafeez (0-43) combined to slow things down a touch, but Warner was still ticking along nicely and two sixes from Hafeez's fifth over restored order.
Warner reached the nineties from 65 balls, but then took 12 deliveries to negotiate his way to 99 before a defensive push took him to three figures and around the square in leaping celebration.
Head was yet to pass 50, but a boundary did the job in the next over and a home-ground hundred was not far behind on the cut shot.
Warner's fourth maximum had put the stand into Australian record territory but the cramping left-hander was eventually out in the 42nd over and carving Junaid Khan (2-61) to point, sparking a chaotic end to the innings that continued with captain Steve Smith (4) falling after two balls.
A Glenn Maxwell cameo alongside Head put the crowd on alert, while the South Australia captain was given a standing ovation from the field when he fell to Hasan, who had the last laugh, but not the loudest.
Sharjeel Khan helped Pakistan to 140-1 before he went for a 69-ball 79 but, though Azam struck his fourth ODI ton, Pakistan never looked like reaching their target and Mitchell Starc (4-42) starred with the ball to ensure a dominant Australia win.