Nemani Nadolo scored two tries as Montpellier beat Northampton Saints 26-17 in the European Champions Cup to keep their hopes of qualifying for the quarter-finals alive, while Johnny Sexton was injured in Leinster's draw at Castres.
A 57-3 drubbing at Leinster last week left the Top 14 high-fliers with a slim chance of advancing as one of the three best-placed runners-up, but Jake White's men did all they can to remain in the tournament in their final Pool 4 game on Friday.
Bulldozing Fiji winger Nadolo claimed a second-half double at Altrad Stadium, while a first-half score from Kelian Galletier and another from Jacques Du Plessis on the hour ensuring Montpellier were always in control.
A converted score from Lee Dickson and late Tom Kessell five-pointer were in vain for the Premiership side, who finish bottom with just two wins from their six games.
Saints felt aggrieved when a superb George North try early in the second half was disallowed by the TMO, who spotted that Ahsee Tuala had stepped on the whitewash in the build-up.
Nadolo, proved to be the difference, also laying on Galletier's try after powering his way through the Saints defence and Montpellier must now wait on other results this weekend to see if they will advance after moving on to 16 points.
Leinster were already assured of top spot and a place in the last eight but they are not guaranteed a home quarter-final following a 24-24 draw at Castres.
The Pro12 side also lost Ireland fly-half Sexton to a leg injury just two weeks before the Six Nations starts, but Robbie Henshaw scored two tries and Dan Leavy's converted score ensured they avoided defeat.