The Jaguars did not even wait for the team to return to Jacksonville to make a change, sacking head coach Gus Bradley.
Hours after a heartbreaking 21-20 NFL loss to the Houston Texans, the Jaguars announced the departure of Bradley with two games remaining in his fourth season.
The loss was the ninth straight for the Jaguars, who dropped to 2-12 on the season. Jacksonville never won more than five games under Bradley.
The Jaguars did not name an interim coach, but that announcement is expected to be made on Monday.
"I thanked Gus Bradley today for his commitment to the Jacksonville Jaguars over the past four seasons," Jaguars owner Shad Khan said in a statement.
"As anyone close to our team knows, Gus gave his staff and players literally everything he had. Our players competed for Gus and I know they have great respect for him, as do I.
"Gus also represented the Jaguars, the Jacksonville community and the NFL in nothing less than a first-class manner as our head coach. That counts for a lot. It is unfortunately evident that we must make a change. I thought it would be best to do it immediately after today's result so Gus can step away, relax and regroup with his family during the Christmas and holiday season."
Khan said general manager Dave Caldwell would explore "all options to hire the best head coach possible to lead" what the owner called "an extremely talented team."
The Jaguars held a 20-8 lead Sunday after Marqise Lee's 100-yard kick-off return with less than seven minutes remaining in the third quarter. But the Texans rallied behind backup quarterback Tom Savage, scoring 10 points in the fourth quarter.