Reigning champion Park Inbee has announced her withdrawal from the Women's British Open as she continues to struggle with a thumb injury.
The South Korean, ranked third in the world, added the Open to her list of honours to complete a career grand slam last year.
But, with the Olympics on the horizon, the 28-year-old is not willing to risk making the issue with her thumb worse.
"This has been an incredibly hard decision for me to make and the reason I've left it to the very last minute," Park said in a statement. "Winning the British Open last year at Turnberry meant so much to me in more ways than you could imagine.
"Since the PGA I've been resting and rehabilitating my left thumb in the hope that I would be right to defend my title next week but it just needs a little bit more time.
"Therefore, I will be unable to attend this year's British Open and now must concentrate on getting healthy and ready to compete for my country at the Olympic Games in Rio."
This year's tournament begins at Woburn Golf Club next Thursday.