Edwin Encarnacion knocked a walk-off home run for the Toronto Blue Jays to seal a 4-3 over divisional rivals the Baltimore Orioles on Friday.
The Blue Jays lost the series opener on Thursday, but bounced back - despite almost throwing away another good start.
They were 2-0 up after the four innings, but were 3-2 down by the time they came out to bat at the bottom of the sixth, with Justin Smoak scoring off a Russell Martin RBI single, before Encarnacion went deep at the bottom of the 10th to seal the win.
The New York Yankees shut out the Detroit Tigers 4-0 after a three-run first inning set them off to the best possible start as they improved to 31-30 for the season.
The Washington Nationals were 9-6 winners at home against the Philadelphia Phillies as Stephen Strasburg scored a club-record 13th-straight winning decision, while the St Louis Cardinals left it late, with a six-run 12th inning sealing a 9-3 win over the Pittsburgh Pirates.
The Chicago Cubs lost for just the 18th time this season as they went down 5-1 to the Atlanta Braves, which proved just their 18th win of the season, as Bud Norris impressed from the mound.
The Tampa Bay Rays beat the Houston Astros 4-3, the Cincinnati Reds were 2-1 winners over the Oakland Athletics, the Boston Red Sox noted their 35th win in an 8-1 triumph over the Minnesota Twins and the Chicago White Sox beat the Kansas City Royals 7-5.
The New York Mets won 2-1 against the Milwaukee Brewers after 12 innings, the San Diego Padres were 7-5 winners over the Colorado Rockies, the Cleveland Indians won 6-2 against the Los Angeles Angels and the Miami Marlins beat the Arizona Diamondbacks 8-6.
Elsewhere, there were wins for the Seattle Mariners, who beat the Texas Rangers 7-5, and the Los Angeles Dodgers, who beat the San Francisco Giants 3-2.
CARPENTER BUILDS CARDINALS WIN
Matt Carpenter had two hits, including his 10th home run, and two walks in six plate appearances as the Cardinals won in 12 innings in Pittsburgh. He scored two runs and drove in three.
EDWIN SEALS WALK OFF
The Blue Jays have been hit and miss this season, but Encarnacion was definitely hitting on Friday, as he crushed a 10th inning pitch for a walk-off home run.
Pirates right-hander Gerrit Cole left the team's home game against the Cardinals in the third inning with muscle tightness in his right biceps. After meeting with Bucs manager Clint Hurdle and a team trainer on the mound, he left the game. He had thrown only 35 pitches and left leading 1-0. Cole will undergo further evaluation Saturday.
ORIOLES OUT TO CONTINUE GOOD START
The Orioles were supposed to be the doormats of the American League East this season, but have surprised everyone by heading into mid-June atop the division. But there ia a long way to go, starting with this four-game series against the Blue Jays -- the trendy preseason choice to win the AL East.
The O's won the opener Thursday, Toronto won Friday. Saturday afternoon, the Orioles will send Mike Wright (3-3, 5.14 ERA) to the hill, coming off seven shutout innings in his last outing against the Royals. The Jays will counter with J.A. Happ, who resurrected his career in Pittsburgh late last season and has continued his success with the Jays this year (6-3, 3.57 ERA).