Australia defensive coach Nathan Grey said the Wallabies will be looking to exploit Ben Te'o's lack of experience on the international stage as the England centre seeks to make his Test debut.
Te'o has only been playing rugby union since 2014 after switching from league, but the 29-year-old is in line to debut under former Wallabies coach Eddie Jones in Brisbane on Saturday.
The New Zealand-born player, who will link up with Premiership outfit Worcester Warriors next season, has impressed in his time with Leinster but Grey said the Australians will be targeting Te'o after being asked about his weaknesses.
"I think just his time in the game," Grey told reporters on Tuesday.
"He's been playing for a number of years now but obviously taking that step up and playing at the international level is a big step and obviously everything gets tested at a high level.
"You've got less time, you've got less space and I suppose your skills under pressure and execution under pressure are obviously the hardest thing to replicate without actually getting out there and playing."
Grey, though, did add: "He's a great talent, he's been playing consistently well.
"He provides a really good strong ball-carrying centre, He's very good defensively and he's got a very good carry, so in terms of preparation for us he is certainly at the sharp end of the queue in terms of making sure we're across what his strengths and weaknesses are."
The opening game of the three-Test series will see former Wallabies international Grey and Jones reunite.
But while he has respect for Jones, the 35-cap international refused to buy into the England coach's claims that Australia struggle defensively.
"I think all defensive systems have flaws in them but it's just a matter of being able to expose them," said Grey, who played under Jones.
"We're very confident in terms of the way we defend as a team and individually.
"That's probably the most important thing, you have to make sure that individual one-on-one technique is up to scratch.
"It doesn't matter how good your system is, if your one on one defence isn't up to scratch, then you're going to be leaking metres and points."