The Los Angeles Dodgers posted the largest Opening Day shutout in MLB history after routing the San Diego Padres 15-0.
Taking to the field for the first time on Monday, the Clayton Kershaw-led Dodgers were relentless as they dealt the Padres their worst season-opening defeat.
The San Francisco Giants were also big winners, easing past the Milwaukee Brewers 12-3 thanks to a binge of home runs at Miller Park.
Daniel Murphy enjoyed a memorable debut, with his 10th-ininning go-ahead double lifting the Washington Nationals over the Atlanta Braves 4-3.
The Toronto Blue Jays topped the Tampa Bay Rays 5-3 for a second consecutive day, the Chicago Cubs shut out the Los Angeles Angels 9-0, the Baltimore Orioles edged the Minnesota Twins 3-2, while the Texas Rangers beat the Seattle Mariners by the same scoreline.
Joey Votto helped the Cincinnati Reds to a 6-2 win against the Philadelphia Phillies, the Oakland Athletics lost 4-3 to the Chicago White Sox and the Colorado Rockies 10-5 Arizona Diamondbacks.
HARPER CONTINUES WHERE HE LEFT OFF
After hitting a league-best 42 home runs last year, reigning National League (NL) MVP Bryce Harper clubbed a homer in his first at bat of the season as the Nationals pipped the Braves.
BACK-TO-BACK-TO-BACK HOMERS, PILLAR PROVIDES ONE FOR THE HIGHLIGHT REEL
One of the Giants' off-season acquisitions, Denard Span, started a string of three home runs in consecutive at-bats. With two men on and two out in the eighth inning, Span crushed a 3-2 fastball off Brewers pitcher Ariel Pena to begin the sequence. Joe Panik and 2012 MVP Buster Posey followed with solo shots off Pena to give the Giants a nine-run lead at Miller Park.
Blue Jays outfielder Kevin Pillar continued his acrobatic defensive plays from last season. Pillar robbed the Rays' Steve Pearce with a great dive and even better manoeuvre to avoid serious injury with the outfield wall.KERSHAW FLEXES MUSCLES
Kershaw - the three-time NL Cy Young Award delivered a gem in the team's rout of the Padres. Kershaw pitched seven scoreless innings, allowing just one hit and one walk while fanning nine. With the performance, Kershaw became the second pitcher ever with nine strikeouts and no more than one hit allowed on opening day; joining the Cubs' Lon Warneke in 1934.
"It was just a fun day," said Kershaw. "Fifteen -- hopefully I can make that stand up."
YANKEES, RED SOX IN ACTION AFTER POSTPONEMENTS
After Monday's postponement, the Houston Astros and the New York Yankees will finally clash in a makeup game on Tuesday as 2015 American League (AL) Cy Young winner Dallas Keuchel heads to Yankee Stadium.
Also originally scheduled for Monday, the Boston Red Sox and the Cleveland Indians are set to face-off. A matchup of Cy Young Award winners David Price and Corey Kluber was postponed to Tuesday due to cold temperatures. The game will also be the final opening day for Red Sox great David Ortiz, who is retiring at the end of the season.