The New England Patriots improved to 9-0 this season after a comeback 27-26 win over the New York Giants in the NFL on Sunday.
Patriots kicker Stephen Gostkowski blasted a 54-yard field goal to give the unbeaten Patriots their win.
The win was especially special for the Patriots, who lost to the Giants in Super Bowl XLII and Super Bowl XLVI.
Tom Brady had 334 yards and two touchdowns after completing 26 of 42 passes.
The Detroit Lions have had little to celebrate this season, but won at Lambeau Field for the first time in 24 years with an 18-16 victory over the Green Bay Packers.
The Packers have lost three straight for the first time since 2008, having started the season 6-0.
The Washington Redskins embarrassed the New Orleans Saints at FedExField, winning 47-14.
Redskins quarterback Kirk Cousins was fabulous with 324 passing yards and four scores, two of which went to tight end Jordan Reed.
The Baltimore Ravens also lost in poor fashion after a facemask penalty on Elvis Dumervil led to their 22-20 defeat against the Jacksonville Jaguars.
It allowed the Jaguars an untimed down and Jason Myers nailed a 53-yard field goal to lift them to victory.
Peyton Manning moved to number one on the NFL's career passing list, but the Denver Broncos fell to a 29-13 loss to the Kansas City Chiefs.
Manning was benched after completing just five of 20 passes and throwing four interceptions.
The Carolina Panthers stayed unbeaten after a 27-10 win over the Tennessee Titans saw them improve to 9-0.
Battling a foot injury, quarterback Ben Roethlisberger guided the Pittsburgh Steelers to a 30-9 win over the Cleveland Browns, throwing for 379 yards and three TDs.
Steelers receiver Antonio Brown had another great day with 10 catches for 139 yards and two touchdowns, and a front flip into the end zone following his second score.
Elsewhere, the Tampa Bay Buccaneers edged the Dallas Cowboys 10-6, the Chicago Bears beat the St Louis Rams 37-13 and the Arizona Cardinals were 39-32 winners over the Seattle Seahawks.
Adrian Peterson ran for 203 yards in the Minnesota Vikings' 30-14 win over the Oakland Raiders and the Miami Dolphins rallied past the Philadelphia Eagles 20-19.