Marcus Lee bought a plot of derelict wasteland in Hackney east London for a reported £70,000.
The architect then spent £330,000 transforming the plot into a luxury five-bedroom home.
The property is now on the market for £2.25 million.
Prices in Hackney have shot up by 17 per cent in the last year and Mr Lee is now set to make sizeable profit.
The glass for the windows cost £20,000 alone.
The contemporary property has won numerous design awards since its completion in 2007.
Among the awards was a Royal Institute of British Architecture award in 2009.
The five-bedroom home has a large open plan ground floor.
Mr Lee is selling the property so he can move on to his next project.
The retro home is very bright an airy and benefits from a lot of natural light.
Mr Lee was also involved in the design of Heathrow's Terminal 1 and Terminal 5.
The eye-catching property has a timber frame design.
The house is located in an industrial cul-de-sac in Hackney.
The average price of a house in this area is £50,000.