A motorway has been partially closed after a serious "multi-vehicle" collision.
Police and paramedics were called to the M40 northbound in Oxfordshire, between junctions 10 and 11, at just before 11.40pm on Saturday.
South Central Ambulance Service said five crews were on scene and six patients were being treated.
A driver who passed the scene said he could see about 30 emergency vehicles at the incident near Cherwell Valley services.
Thames Valley Police said: "The northbound carriageway of the M40 between junction 10 and junction 11 is currently closed after a multi-vehicle RTC.
"We would advise motorists to avoid the area at this time while emergency services are at the scene.
"The road is expected to be closed for a number of hours so please find alternative routes."