Twenty-five people have been killed in a bombing at Egypt's main Coptic Christian cathedral, and another 49 wounded, according to Egyptian state television, in the second deadly attack to hit Cairo in two days.
Egypt's official Mena news agency said an assailant lobbed a bomb into a chapel close to the outer wall of St Mark's Cathedral, seat of Egypt's Orthodox Christian church and home to the office of its spiritual leader, Pope Tawadros II.
On Friday, six policemen were killed in a bomb attack in Cairo claimed by a group suspected by authorities of links to the outlawed Muslim Brotherhood.
There was no immediate claim of responsibility for Sunday's attack, which bore the hallmarks of Islamic militants fighting the government of President Abdel-Fattah el-Sisi.
As defence minister, he led the July 2013 ousting of Mohamed Morsi, an elected Islamist president who hails from the Brotherhood.
Islamic militants launched a wave of attacks on security forces and Christians in response, as the government waged a sweeping crackdown on Morsi's supporters and other activists.