If you're lucky, you have the sort of neighbours who will take in your packages, lend you their lawnmower and keep an eye on your home while you're away.
Plenty of people, though, are a lot less fortunate. In fact, one in five say they've been involved in a dispute with their neighbours in the last year alone.
Noise is the most frequent problem, whether it's barking dogs, late night parties or loud arguments.
Just last week, for example, the Liverpool neighbours of Stephanie Davis and Jeremy McConnell lost patience with the pair for continual screaming matches, and started complaining to Stephanie's parents.
For many people, the problem is parking. In what surely must be the most extreme example, residents of a cul-de-sac in Stockport, Greater Manchester, have been fighting for over 30 years over the limited number of spaces.
The situation's got so bad that their double-parking can be seen by Google Earth from space.
And for others, it's garden disputes that drive them crazy, from smelly barbecues to the dreaded Leylandii hedge.
If this doesn't help, and they are renting the property, you can approach their landlord with your complaint.
If all else fails, you can call your local environmental health department or planning department - or even the police, especially if there's racial or sexual harassment involved.
You can, of course, go through the courts - but beware, as this can be a very long and costly route. In one case earlier this year, for example, it was revealed that a Northumberland solicitor had got so angry about a shed that he believed was blocking his right of way that he racked up legal bills of £140,000 trying to get it removed.
To read more stories about neighbours from hell take a look at the slideshow below.