Alcohol poisoning among girls is contributing to a rise in teenage toxic incidents, research suggests.
Experts analysed GP records and found a 27% rise in such cases - including accidental, deliberate self-harming and alcohol poisoning - between 1992 and 2012.
There were 17,862 cases of poisoning among UK teenagers between 1992 and 2012, the data, published in the journal Injury Prevention, showed.
Looking at the number of poisonings occurring in 100,000 young people year terms, experts found a rise from 264.1 new cases per 100,000 person years to 346.8 per 100,000.
The largest increases were for intentional poisonings among 16- to 17-year-old-girls and for alcohol-related poisonings among 15- to 16-year-old girls, both of which roughly doubled.
Between 2007 and 2012 almost two-thirds (64%) of poisonings were recorded as intentional, and 16% were related to alcohol.
Girls were significantly more likely to suffer from poisoning, the study found, with the rate of poisoning in boys and young men less than half of that in girls and young women. Intentional poisonings were 80% lower in boys and young men than girls.
And alcohol-related poisonings were 10% lower in boys and young men.
The research, from the University of Nottingham, also found that youngsters living in the most economically deprived regions were two to three times more likely to poison themselves than those in the least deprived.
Poisoning is one of the most common causes of death among teenagers worldwide, with much of it related to self-harm.
The authors said: "One potential explanation for the increase in alcohol poisonings over time is increased availability, with the relative affordability of alcohol in the UK increasing steadily between 1980 and 2012, licensing hours having increased since 2003, and numbers of outlets increasing alongside alcohol harm."
But they urged caution over the interpretation of their findings too, adding: "We must consider whether this (the increasing rates seen among young women) reflects real changes, increased health-seeking behaviour or changes in GP coding practices, or popular trends, such as clinicians perceiving intentional poisonings as more frequent and therefore recording events as such."
A second study published in the Archives of Disease in Childhood found that more than half of UK toddler deaths from unintentional drug poisoning are due to methadone.
Experts looked at data on childhood poisonings and admissions to intensive care for unintentional poisoning between 2001 and 2013.
During this period, 28 children under the age of four died in England and Wales as a result of unintentional poisoning with a prescribed drug. Methadone, which is used by heroin addicts to help kick their drug habit, was responsible in 57% of these cases.
Between 2002 and 2012, 201 toddlers were admitted to intensive care as a result of unintentional poisoning with prescribed drugs.
Sedatives accounted for nearly one in five (19% or 22 cases), while methadone accounted for 17% or 20 cases.