There's over 1,800 items already reduced in price, with big-name brands including No7, YSL, Clinique, Oral-B and Dyson.
Some of the biggest savings can be found on Christmas gift sets, particularly those featured in Boot's Star Gifts, which change weekly.
One gift set that has caught our eye this week is the Clinique Let It Glow 5-Piece Beauty Gift Set. Worth a whopping £123.16, you can buy it for just £45 - that's a saving of over £75!
It's limited-edition, exclusive to Boots and selling fast, so you'll have to be quick if you want to snap up this beauty bargain.
Why we rate it
This set features five of Clinique's best-sellers, including three full-size products.
There's a Dramatically Different Moisturizing Lotion (£37), a Moisture Surge Overnight Mask (£38.50) and a High Impact Mascara, along with deluxe miniatures of its famous Almost Lipstick in Black Honey (£24) and All About Clean Rinse Off Foaming Cleanser (£25).
The skincare products will help keep your complexion dewy and radiant throughout the winter months, while the two make-up must-haves are ideal for Christmas party season.
Our top pick? The Black Honey Lipstick is renowned for being flattering on all skin tones, providing a sheer berry burst of colour with just one swipe, while the Moisture Surge Overnight Mask is a godsend for skin needing a serious hit of hydration, especially during cold weather.
What the reviews say
A handful of reviews have begun trickling in, with five-star rating across the board from customers impressed with the value for money of this set.
"Been wanting to try Clinique for a while and this set is amazing and so worth the price, delighted with everything in tin."
"I picked this star gift up today its exceptional value and the packaging is a bonus so happy with it my daughter will love it."
"This is a great offer."
Shop it now: Clinique Let It Glow 5-Piece Beauty Gift Set | £45 (Worth £123.16) from Boots
It's not the Clinique gift set on offer either. This November, there's plenty more to shop in the Black Friday sales containing the brand's biggest hits. Here's a few more of our top picks:
Clinique's Most Loved: 7-Piece Beauty Gift Set | £62.50 (Was £125) from Boots
Clinique Bestsellers Beauty Gift Set | £36 (Worth £59.08) from Boots
🛍️ Best Star Gifts deals - get 50% off
🛍️ Best fragrance deals - save up to £48
🛍️ Best electrical deals - save up to £275
🛍️ Best advent calendar deals - get 50% off
🛍️ Best skincare deals - save up to £78
🛍️ Best make-up deals - get up to 50% off