The Andrew Neil Show is one of the casualties of the BBC cuts, it has been confirmed.
The former Sunday Times editor has been one of the BBC's top political broadcasters for many years and has presented This Week and Daily Politics.
The corporation has announced a further 70 job cuts in BBC News on top of the 450 announced earlier this year, taking the total number of job losses up to 520.
Show's host Andrew Neil before The Chancellors Debate on the BBC current affairs programme The Daily Politics at BBC Millbank in London.
The Andrew Neil Show axed amid BBC cuts
Piers Morgan (L) and Andrew Neil attending the Grand Final of Miss Great Britain 2007, held at Grosvenor House hotel in central London.
LONDON, ENGLAND - JANUARY 22: Andrew Neil attends The Spectator Parliamentarian Of The Year Awards at Rosewood London on January 22, 2020 in London, England. (Photo by David M. Benett/Dave Benett/Getty Images for The Spectator)
Andrew Neil arrives for the memorial service for photographer Terry O'Neill at The Grosvenor Chapel, in London's Mayfair district.
Broadcast and journalist Andrew Neil with his honorary degree in the East Quadrangle at Glasgow University after receiving it in a ceremony.
Andrew Neil, presenter of Sunday Politics, arrives at BBC Broadcasting House in London.
Andrew Neil arrives at the 2015 Costa Book Awards at Quaglino's, London.
Broadcaster Andrew Neil (left) and Michael Portillo arrive for the funeral service of Baroness Thatcher, at St Paul's Cathedral, central London.
Bishop Welby chats with Andrew Neil after collecting his award for Peer of the Year at this year's Spectator Magazine's Parliamentarian of the Year Awards, in central London.
PHOTO ONLY TO BE USED TO ILLUSTRATE MEMORIAL BURNET - NO ARCHIVING PERMITTED Handout photo issued by ITN of Andrew Neil attending a service of thanksgiving celebrating the life of former ITN presenter Sir Alastair Burnet at St-Martins-in-the-Fields, Trafalgar Square, London.
Andrew Neil during the Cartier International Polo day, held at the Guards Polo Club in the Great Park, Windsor, Berkshire.
Picture date: Sunday July 25, 2010. Photo credit should read: Steve Parsons/PA Wire
BBC journalist Andrew Neil (front) and (left to right) Business Secretary Lord Mandelson, Scottish National Party Business Secretary John Swinney, Liberal Democrat Shadow Business Secretary John Thurso, and Conservative Shadow Business Secretary Ken Clarke ahead of recording BBC2's Election Daily Politics Debate, at Millbank Studios, in Westminster, London.
Show's host Stephanie Flanders, BBC Economics Editor and Andrew Neil before The Chancellors Debate on the BBC current affairs programme The Daily Politics at BBC Millbank in London.
Andrew Neil and Sir Jackie Stewart share a joke during the Johnnie Walker Blue Label Great Scot Award at Boisdale of Belgravia, London.
Ken Livingston (L) and Andrew Neil arriving at the Sir David Frost Summer Garden Party 2009, Carlyle Square in Chelsea, central London.
Andrew Neil and girlfriend arriving at the Sir David Frost Summer Garden Party 2009, Carlyle Square in Chelsea, central London.
Discover More Like This
BACK TO SLIDE
Neil's self-titled political programme has been off air during the coronavirus crisis but will not return to screens.
A BBC spokeswoman said: "We remain committed to Andrew Neil's in-depth interviews (as well as the Budget, US Election and other Specials).
"The Andrew Neil Show will not be returning but we're in discussions about a new interview series on BBC One."
Politics Live, which is currently only airing on Wednesdays because of the pandemic, will return four days a week from Monday to Thursday.
However, Neil is not expected to present the show on a regular basis.
The BBC announced in 2016 that it needed to save £800 million, with around £80 million of that figure coming from news.
The corporation has since announced plans to reduce its "pool of presenters", while more correspondents will increasingly be asked to work across a range of content.
Victoria Derbyshire's BBC Two programme has been axed and it was previously announced that Newsnight, 5Live and Today would be affected as part of cost-cutting plans and an effort to reach the young.