The mother of One Direction star Louis Tomlinson has died aged 43, her family have confirmed.
Johannah Deakin died on Wednesday morning after suffering from leukaemia.
The mother of seven had been cared for at University College London Hospital since May before being moved to the Royal Hallamshire Hospital in Sheffield for the last few weeks of her life.
In a statement issued by Tomlinson's representative, her family said: "It is with immeasurable sadness that Johannah Deakin's family said goodbye to Johannah in the early hours of Wednesday 7th December 2016.
"Earlier this year Johannah was diagnosed with a very aggressive form of leukaemia that required immediate and continuous treatment. We respectfully request that the family are given time and space to grieve in private."
Deakin's husband, Dan Deakin, paid tribute to his wife, calling her "incredibly selfless" and a "truly amazing mother".
As well as 24-year-old Tomlinson, she leaves behind six other children, Lottie, 18, Felicite, 16, and two sets of twins, Phoebe and Daisy, both 12, and Ernest and Doris, both two.
Mr Deakin: "She would always look to put other people before herself.
"She desired nothing more than for everyone around her to be happy and loving. She worked tirelessly on numerous charity campaigns, creating memories for many individuals and their families.
"It wasn't uncommon for Johannah to hear through the media of an individual in need of assistance, and she would immediately make it her objective to get that person what they often desperately needed, and rarely without success.
"These are the things that made Johannah happy and content in life, and all of which for me made her simply the perfect wife and best friend to face each day with.
"I thoroughly loved walking through life with her, and though five years was far too short a time, during that time we had so many lifetimes' worth of happiness, adventures and memories."
Mr Deakin added: "We would like to send our sincere thanks to Professor Steve Mackinnon and his team at University College London Hospital, where Johannah was hospitalised since May. And during the last few weeks, Professor John Snowden and his colleagues at Royal Hallamshire Hospital, Sheffield."
Tomlinson, who had been scheduled to make a surprise appearance on The X Factor this weekend, will still perform in memory of his mother, his management confirmed.