Celebrity chef James Martin will swap the kitchen for the This Morning sofa to host the show throughout the summer.
He will be joined by Countryfile presenter Anita Rani to front the ITV daytime show every Friday starting on July 22.
The pair will take over the Friday slot from Eamonn Holmes and Ruth Langsford, who will move to hosting Monday to Thursday while regular hosts Phillip Schofield and Holly Willoughby are on their annual summer break.
James admitted he would "do his best", but said he still finds live television "daunting".
He said: "It can be nerve wracking at times because you're always a little unsure about what could happen next!
"I can handle the food items and talk about that no problem, but to go from such light and shade topics... it's one of the toughest gigs in television without a shadow of a doubt and you realise what pros they are that do this job. But I'll do my best, as that's all I've done for the last twenty years!"
He was previously a guest host on This Morning earlier in the year.
Anita, who competed in last year's Strictly Come Dancing, said it was a "brilliant way to spend Fridays over the summer".
She said: "Many hours of my life - certainly when I was a student - have been spent watching this daytime TV institution, so I genuinely cannot wait to see what's in store over the coming weeks."
She added: "And I'll use the opportunity to pick James Martin's brilliant cooking brain for top tips and get misty-eyed over Yorkshire with him. Roll on Friday!"
During their first show they will speak to actor Brendan O'Carroll, discuss the latest beauty trends and learn some allotment tips, with Martin showing viewers his own vegetable patch.
Former Saturday Kitchen host James will also cook two summer inspired dishes with seasonal tomatoes.
This Morning's Editor, Martin Frizell said: "James and Anita are both brilliant hosts in their own right and certainly have the skills suited for the varied and fast-paced nature of This Morning. Plans this year will certainly keep our viewers entertained across the summer weeks."