EastEnders fans will finally see Peggy Mitchell reunited with her sons Grant and Phil, but the 10-year wait for a family reunion is doomed to end in heartbreak.
In Monday's episode of the BBC One soap, Mitchell matriarch Peggy, played by Dame Barbara Windsor, arrived back in Albert Square.
In Tuesday's instalment, she will learn her cancer has spread and nothing more can be done.
News that his family needs him reaches Grant (Ross Kemp) and, worried about his mother, he rushes back to Walford.
Sparks are set to fly as the turbulent relationship between Grant and his older brother Phil (played by 57-year-old Steve McFadden) comes to the fore once more.
Can they put their differences aside for the sake of their dying mum?
Documentary maker Kemp, 51, was a full-time member of the cast for nine years until 1999.
He will make his long-awaited comeback as Grant after a 10-year absence for Dame Barbara's final scenes.
The EastEnders stalwart, 78, is leaving the show for good, and her famous character will be killed off.
Dame Barbara made her début in EastEnders as Peggy Mitchell in 1994.
Talking about his decision to reprise the role, Kemp said it would be a fitting end for Peggy.
Over the years, Grant has been involved in some of the soap's classic storylines, including his fraught marriage to Tiffany (played by Martine McCutcheon).
His return is likely to heighten the drama as Albert Square is now the residence of Grant's ex-wife Sharon (Letitia Dean).
She had an affair with Grant's older brother Phil in the early 1990s before marrying Phil decades later.
The so-called "Sharongate" storyline is one of the most memorable in the Walford-set soap's history.
But the conflict does not end there because Phil's ex-wife Kathy Sullivan (Gillian Taylforth) had an affair with Grant.
She is also a reminder of the Mitchell brothers' turbulent past and present in Albert Square.
Peggy Mitchell will be given an impressive send-off with a selection of BBC specials on May 17, the night her final ever episode of EastEnders is broadcast.