Students from Cambridge's Peterhouse college stormed to victory over their Oxford rivals, claiming the title of University Challenge.
The team won the highbrow BBC2 quiz for the first time, beating Oxford's St John's College by 215 points to 30. They also beat them during the show's quarter-finals.
The feat was a historic third consecutive win for Cambridge over Oxford.
Commenting on the result, host Jeremy Paxman, said: "You can do much better than that St John's as we've seen in many a previous match, but someone has got to win, and Peterhouse, that was a storming performance. Another storming performance from you."
Presenting the trophy was mathematician and Simonyi Professor for the Public Understanding of Science at Oxford, Marcus du Sautoy.
He said: "I thought it was a phenomenal performance. But I am really impressed by how many maths questions there were.
"You're probably cursing the fact that there's a mathematician giving away the trophy, there were so many."
The winning team was captained by the final's only female contestant, Hannah Woods, a history PhD student, and also featured Thomas Langley, who is studying history, Oscar Powell, a student of geological sciences, and Julian Sutcliffe who also reads history.