The brother and sister who age too fast

Despite there being only 155 known cases worldwide, a brother and sister both live with progeria – an incredibly rare disease that makes them age too fast.

Siblings Michiel and Amber Vandeweert have progeria, a genetic condition characterised by the signs of accelerated and premature ageing.

Experiencing problems with their bones, teeth and hair growth, patients with progeria have a very short life expectancy with most not seeing out their teen years.

But that hasn't stopped Michiel, 20, and Amber, 12, living their best life together - the inspirational siblings from Belgium have truly defied all odds up to this point and show no signs of slowing down.

Watch their story in the video above.