Lloyds Banking Group is to axe 450 jobs in a move that will mainly affect back office staff.
The lender chalked the move up to organisational changes that will help it "adapt and evolve to support changes in customer behaviour".
A spokeswoman said branch closures were not on the cards and the decision was in line with its current strategy.
Lloyds said it was also creating 255 new roles as part of the shake-up, and focused on a net figure of 195 job losses.
Lloyds said it would try to redeploy affected staff where possible.
"The group's policy is always to use natural turnover and to redeploy people wherever possible to retain their expertise and knowledge within the group," the bank said.
"Where it is necessary for employees to leave the company, we will look to achieve this by offering voluntary redundancy. Compulsory redundancies will always be a last resort.
"Today's announcement involves making difficult decisions and we are committed to working through these changes in a careful and sensitive way."