The cost of playing Euromillions is to increase to £2.50 a line.
In addition, players must choose from an extra number under changes that will decrease the odds of winning the jackpot but promise bigger prizes and double the number of UK millionaires.
Camelot, one of the 10 operators of the European-wide game, announced the price of a line will go up by 50p to £2.50 from September to "reflect all of the community-wide and UK-only enhancements" and up to Euros 2.50 elsewhere.
Players will still pick five main numbers from one to 50 and two lucky stars, now from one to 12 rather than 11.
The extra lucky star will lessen the chance of winning the jackpot from approximately one in 117 million currently to one in 140 million, but Camelot said the overall odds of winning any prize on Euromillions remained at 1 in 13.
Camelot said the changes would bring bigger jackpots more often with higher starting figures of £14 million and more than twice as many jackpots of more than £50 million a year.
There would also be bigger promotional draws offering jackpots of around £100 million, and new "must-be-won" European Millionaire Maker events, the first of which is expected to take place at the end of October with the creation of 25 extra millionaires.
Local UK "enhancements" will include at least two guaranteed UK millionaires in every draw through the UK Millionaire Maker, making double the current number of guaranteed UK millionaires a year at 208.
Camelot consumer and retail director Sally Cowdry said: "Euromillions has always captured the UK public's imagination with its exhilarating jackpots and numerous multimillion-pound winners - boosting returns to Good Causes in the process.
"It's now time to re-energise the game and take it to the next level and these fantastic enhancements will do just that, helping us to deliver even more for our players and UK Good Causes in the years to come."
Tickets for the first new Euromillions draw on September 27 will go on sale on September 24.
Changes to the National Lottery Lotto draw last year saw the number of balls increase from 49 to 59 and the chance of winning the jackpot decrease from one in 14 million to one in 45 million.
Biggest UK lottery winners
Biggest UK lottery winners
Colin and Chris Weir, from Largs in Ayrshire scooped 161 million in the EuroMillions draw after several rollovers in 2011. They are the biggest British lottery winners in history.
Adrian Bayford, who won an astonishing £148m on the Euromillions with his wife Gillian, had to shut up the music shop he owns, because people targeted it with requests for money.
One British ticket won £113,019,926 in October 2010 but decided not to go public.
Car mechanic and racing driver Neil Trotter scooped a staggering £107.9 million jackpot on the Euromillions lottery in March 2014.
Dave and Angela Dawes won £101 million on the EuroMillions in 2011. It was only the third time the couple, from Wisbech, Cambridgeshire, had played the lottery. The couple are said to have since split up.
The sum was won in May 2010 but the winner kept their identity a secret.
One lucky British ticket-holder picked up a £81million EuroMillions rollover but remained anonymous.
Nigel Page and Justine Laycock from Cirencester bagged a £56 million jackpot back in February 2011. On winning the jackpot, Page said: 'I'd already checked my National Lottery account and had seen I'd won £55 on Lotto when I decided to buy two Lucky Dips for the big EuroMillions jackpot on Friday.'
One lucky winner won shy of 50 million but chose to remain anonymous.
Les and Sam Scadding from Newport, South Wales, and a syndicate of seven Liverpudlian call-centre workers shared a staggering £91 million in November 2009. Les, an unemployed mechanic, was £68 overdrawn on the day he bought his ticket, while the Liverpool syndicate only started playing EuroMillions together four months before their win.
Carrington, 22, from Stapleford in Nottingham, banked £45 million after matching all five numbers and two Lucky Stars in a EuroMillions draw in February 2012. The Iceland supervisor said she planned to marry painter fiancee Matt Topham, 22, following the Lucky Dip win.
Husband and wife Gareth and Catherine Bull have fairly modest spending plans despite their £40.6 million jackpot win in January. Speaking about what she planned to do now that she was rich, Catherine explained that she intended to use part of their winnings to replace the carpet on her upstairs landing...
Angela Kelly became one of the biggest lottery winners in UK history back in 2007, after scooping a £35 million EuroMillions jackpot. This is estimated to earn £5,000 a day in interest alone, meaning she's unlikely to ever be short of cash.
In June 2009, 74-year-old Brian Caswell got the surprise of his life when he took his lottery ticket to his local newsagent and discovered he'd won almost £25 million.
Belfast housewife Iris Jeffrey, 58, was the lucky holder of the record 20.1 million rollover lottery winning ticket back in 2004.
Jeffrey, 58, a cancer sufferer, only realised three weeks after the draw took place that she had won the jackpot after organisers Camelot pleaded for the person holding the prize ticket to come forward and claim the prize.
Stephen Smith and his wife Ida from Hemel Hempstead, Herts, won nearly 19 million in the National Lottery. Mr Smith said he would give up his winnings if he could have his health and the chance to live a longer life with his wife.