The Government is to be accused of being "fundamentally dishonest" about its policies towards disabled people.
TUC general secretary Brendan Barber will tell a conference that disabled workers are being hit more than other groups by the coalition's austerity cuts.
He will tell the TUC's Disabled Workers Conference: "No group of people is more affected by the Government's savage, ideological austerity than disabled workers. It's no exaggeration to say that when it comes to disability, there is a fundamental dishonesty about Government policy.
"The coalition is keen to promote the language of fairness and is keen to stress the opportunities available to disabled people, but the truth could not be more different. Nowhere is the dichotomy between rhetoric and reality starker than when it comes to benefits - a lifeline for so many disabled people.
"As the right-wing press peddles its demeaning myths about workshy scroungers, the Government is slashing £17 billion from the welfare budget. It is the poorest and most disadvantaged people who are suffering the consequences."
Mr Barber will say that the Government's welfare reforms are causing "immense damage".
Meanwhile, disabled workers facing redundancy because of the closure of Remploy factories have staged a protest outside a charity.
Dozens of workers pitched tents outside the London offices of Disability Rights UK as part of their protest against plans to close Remploy factories across the UK with the loss of jobs.
Unions have accused the Government of planning to close all 54 Remploy sites with the loss of 2,800 disabled workers' jobs.