The New England Patriots will begin their Super Bowl defence at home to the Kansas City Chiefs on September 7.
The 2017 NFL schedule was released Thursday and the season will begin at Gillette Stadium in Foxborough, Massachusetts.
The second season for Dallas Cowboys quarterback Dak Prescott and running back Ezekiel Elliott starts at home against a division rival.
Travelling to AT&T Stadium in week one to face the Cowboys on Sunday, September 10 are the New York Giants.
The Los Angeles Chargers will have to wait a week before they officially make their debut at StubHub Center in California.
The first season for the LA Chargers starts in Denver as the second of two Monday night games in week one.
The Chargers and Broncos will follow the New Orleans Saints playing the Minnesota Vikings.
There are several marquee matchups, including a Super Bowl rematch on October 22 when the Patriots play host to the Atlanta Falcons at Gillette Stadium.