George Kruis will make his return from injury against Argentina at Twickenham on Saturday, in an England team showing four changes following last weekend's victory over Fiji.
Kruis missed the wins over South Africa and Fiji due to an ankle problem, but makes a timely comeback this weekend with fellow lock Joe Launchbury absent through suspension.
Tom Wood has also been recalled to England's pack, with Teimana Harrison dropping to an otherwise unchanged bench, while Mike Brown and Jonny May are predictably included in the back three after sitting out the Fiji fixture.
"Selection was tough this week but it shows how much depth we are developing," said head coach Eddie Jones.
Argentina finished fourth in this year's Rugby Championship, but Jones claimed the Pumas' position did not reflect their performances.
"This game against Argentina is a big step up for us as they were probably the second best team in the Rugby Championship and played some exceptional rugby," added the Australian, who has yet to suffer defeat as England coach.
"They are a quality team, have power in the forwards, speed and guile in the backs as well as great experience. We're looking forward to a great challenge against them."
England: Mike Brown, Jonny May, Jonathan Joseph, Owen Farrell, Elliot Daly, George Ford, Ben Youngs; Mako Vunipola, Dylan Hartley, Dan Cole, Courtney Lawes, George Kruis, Chris Robshaw, Tom Wood, Billy Vunipola.
Replacements: Jamie George, Joe Marler, Kyle Sinckler, Charlie Ewels, Teimana Harrison, Danny Care, Ben Te'o, Henry Slade.