A car leaving a parking lot at Martinsville Speedway struck pedestrians following Sunday's NASCAR Sprint Cup race.
The post-race incident injures 22 people after Jimmie Johnson won the Goody's Fast Relief 500.
In a statement released, NASCAR said: "Multiple individuals were struck by a vehicle, and the driver has been taken into police custody.
"Several people were treated on-site by emergency workers in the infield care centre while others have been transported to a nearby hospital.
"We will monitor the situation closely with local authorities, and work with them to provide updates."
Witnesses described a scene of chaos, as law enforcement and rescue workers descended on the scene near the track's helipad.