Pat Lambie and Willie le Roux are back in the South Africa squad for their final two games of the Rugby Championship against Australia and New Zealand next month.
Lambie suffered concussion in the defeat against Ireland back in June and has not played for his country since, but the fly-half will be assessed ahead of a potential international comeback in the clash with the Wallabies in Pretoria on October 1.
Le Roux, who has also not featured for the Springboks since the series triumph over Ireland, returns to a 31-man squad after the full-back fulfilled his commitments with Japanese club Canon Eagles.
Lood de Jager and Julian Redelinghuys are recalled by Allister Coetzee after the duo recovered from injuries, but Lourens Adriaanse misses out against the Wallabies and newly-crowned champions New Zealand a week later.
Coetzee said: "It's great to have players with the experience of Pat and Willie back in the squad. The same goes for Julian and Lood, both of whom have played very well for us this year and will add something to the pack.
"Pat has been included in the squad so that our medical and conditioning team can get first-hand feedback.
"We want to ascertain his readiness and confidence for international rugby or whether he rather needs to play another match in the Currie Cup for the Cell C Sharks."
The Springboks have lost three games in a row after starting the competition with a win against Argentina.
South Africa squad: Willem Alberts, Damian de Allende, Lood de Jager, Juan de Jongh, Faf de Klerk, Pieter-Steph du Toit, Eben Etzebeth, Johan Goosen, Bryan Habana, Francois Hougaard, Elton Jantjies, Steven Kitshoff, Vincent Koch, Jaco Kriel, Jesse Kriel, Pat Lambie, Willie le Roux, Francois Louw, Lionel Mapoe, Malcolm Marx, Bongi Mbonambi, Oupa Mohoje, Franco Mostert, Tendai Mtawarira, Lwazi Mvovo, Trevor Nyakane, Rudy Paige, Julian Redelinghuys, Morne Steyn, Adriaan Strauss, Warren Whiteley.