Wimbledon was stunned on Saturday as defending champion and three-time winner Novak Djokovic was dumped out in the third round by Sam Querrey, but Andy Murray's campaign remained on track.
In a match heavily punctuated by numerous rain delays, top seed Djokovic was surprisingly beaten 7-6 (8-6) 6-1 3-6 7-6 (7-5) by world number 41 Querrey.
The Serbian's exit blows the top half of the draw wide open, with Milos Raonic and Kei Nishikori the likely beneficiaries following their respective wins on Saturday.
Murray is in the opposite end of the draw, but the departure of Djokovic will be a further boost to his ambitions after a comfortable 6-3 7-5 6-2 win over John Millman.
QUERREY ENDS DJOKOVIC SHOT AT GOLDEN 2016
Having already won the Australian Open and French Open - the latter of which completed a career Grand Slam - Djokovic was aiming for a historic feat of securing all four majors and Olympic gold in a calendar year.
However, the Serbian suffered a first defeat in 31 grand slam matches at the hands of Querrey - the first American to beat a world number one in a major since Andre Agassi overcame Lleyton Hewitt in the 2002 US Open semi-final.
After the defeat Djokovic hinted he was not at 100 per cent physically, and announced he would not take part in Serbia's Davis Cup quarter-final against Great Britain this month.
It will be a bitter blow for the 12-time grand slam winner, and, although he confessed to needing a break, he will no doubt be back to set things right.
MURRAY, NISHIKORI AND RAONIC ADVANCE
A routine straight-sets victory saw Murray, now the highest seed remaining in the competition, cruise past Millman and into the fourth round.
Nishikori had a similarly straightforward 7-5 6-3 7-5 win against Andrey Kuznetsov, but the fifth seed's toughest test yet will come when he faces Marin Cilic - a 6-3 6-3 6-4 winner against Lukas Lacko - for a place in the quarter-finals.
Sock dropped just one service game but Raonic's clinical approach to the tie-breaks saw him come out on top 7-6 (7-2) 6-4 7-6 (7-1), with David Goffin waiting in the next round after the Belgian dispatched of Denis Istomin 6-4 6-3 2-6 6-1.
Steve Johnson came from one set down to beat Grigor Dimitrov 6-7 (6-8) 7-6 (7-3) 6-4 6-2, setting up a match with Roger Federer.
DEL POTRO, TSONGA WITH WORK TO DO
Juan Martin del Potro overcame fourth seed Stan Wawrinka in the second round but was trailing to Lucas Pouille 6-7 (4-7) 7-6 (8-6) 7-5 when play was stopped due to bad light.
Jo-Wilfried Tsonga picked up a crucial tie-break win to pull a set back against John Isner, but at 7-6 (7-3) 6-3 6-7 (5-7) behind he will still have plenty to do when he returns to the court.
Richard Gasquet led Albert Ramos-Vinolas by two sets to one when it became too dark to continue, while Nick Kyrgios and Feliciano Lopez are level at one set apiece.
MAHUT LIKE A FRENCH WINE
With a 7-6 (7-5) 6-4 3-6 6-3 victory over fellow Frenchman Pierre-Hugues Herbert, Nicolas Mahut, at 34 years and 171 days old, became the oldest man to reach the round of 16 at a major for the first time in the Open Era.
Mahut had only once featured in the third round at Wimbledon once before back in 2006, though he has also reached that stage in the Australian Open and French Open.
Next up for the Frenchman is Djokovic's conqueror, Querrey.