England begin their campaign at the Stade Velodrome, Wales will visit the Stade de Bordeaux, the Republic Ireland kick off at the Stade de France, and Northern Ireland will head to Nice.
Here's our guide to the venues of Euro 2016.
Stade de Bordeaux
An area more famous for its wine than football, the capital of the Aquitaine region will be the picturesque venue of four group stage matches and a quarter-final. Built at a cost of 184 million euros (£146.5 million), the new home of Bordeaux is located between a man-made lake and the Garonne river in the north of the city.
Easily the smallest host city of Euro 2016, the rebuilt stadium could almost fit the entire population of Lens inside it. The Stade Bollaert-Delelis was originally opened in 1933 and the latest renovation work was completed last August on the home of Ligue 2 side Lens. England v Wales is one of four matches being held there.
Stade Pierre Mauroy
This forward-thinking and cosmopolitan city has a stadium boasting a retractable roof and 50,000 capacity. Open since August 2012, the stadium four miles south-east of the city centre is twice the size of Ligue 1 side Lille's previous homes and will host six matches during Euro 2016.
Stade de Lyon
France's third-largest city has a stadium befitting that size and status, with the 59,000-seater Stade de Lyon opened at the start of the year. Part of a complex stretched over 50 hectares, it replaces the Stade de Gerland, a 1998 World Cup venue, and will host one of the Euro 2016 semi-finals.
A 267 million euro (£212 milion) makeover has transformed the ground into a state-of-the-art home for Marseille. First opened in 1937, the pre-Euro 2016 makeover was done with the team still playing there and was finished in October 2014. It has hosted matches at two previous World Cups and European Championships, with a semi-final the last match being held there this summer.
Stade de Nice
France's most popular tourist destination away from the capital will welcome supporters to the eco-friendly Stade de Nice this summer. Opened in September 2013, the stadium draws over three times its own energy requirements from more than 4,000 solar panels. It has its own geothermal installation for heating and rain water channelled from the roof is used to water the pitch.
Parc des Princes
A petition for a major football club to be established in the French capital drew 20,000 signatures and led to Paris St Germain being founded in 1970. Two years later their Parc des Princes home opened - the third stadium to have been built on the site. Now with a boosted capacity of 45,000, the pre-Euro 2016 preparations have improved services for fans - welcome news to Northern Ireland supporters as their side face world champions Germany there.
Stade de France
Football became a major part of Saint-Denis' facelift when an 80,000-capacity stadium was constructed to host the 1998 World Cup final. It is has subsequently hosted a variety of sports and events, as well as becoming home of the French national team. The Stade de France, six miles north of central Paris, will host seven matches, including the final, and will be subject of heightened security after the terror attacks at the stadium in November.
Stade Geoffroy Guichard
A stadium nicknamed the Le Chaudron (the Cauldron) due to the intense fervour built here. Situated north of the city centre, a facelift has helped enlarge its capacity in time to host four matches, including England's final group match against Slovakia, and a last-16 clash.
Stadium de Toulouse
The smallest stadium in use at this summer's championships, it was nicknamed 'mini Wembley' shortly after it opened in 1937. It hosted World Cup matches the following year, so too during the 1998 edition, and underwent upgrade work to get it ready in time for Euro 2016, when Wales' clash with Russia will be among four matches hosted there.