The South African Doping Control Laboratory has become the latest centre to be suspended by the World Anti-Doping Agency (WADA).
After centres in Moscow, Beijing and Lisbon suffered similar punishments last month, the facility in Bloemfontein has had its accreditation stopped until September 30.
WADA's decision takes effect immediately and will require all samples previously destined for Bloemfontein to be transported to another accredited laboratory.
A statement announcing the decision read: "During the period of suspension, the laboratory shall address all non-conformities identified in its External Quality Assessment Scheme (EQAS) program and any other non-conformities identified in the course of WADA site visits during the suspension period.
"If the laboratory satisfies the Disciplinary Committee in meeting these requirements, the laboratory may apply for reinstatement prior to 30 September."
The centre has 21 days to appeal WADA's decision with the Court of Arbitration for Sport.