Jack Butland looks set to miss out on a place in England's Euro 2016 squad after it was confirmed he sustained a fractured ankle in Saturday's friendly against Germany.
The Stoke City goalkeeper was taken off on a stretcher shortly before half-time of England's 3-2 win in Berlin, after appearing to hurt himself while making a save.
Butland, who was standing in for injured first-choice keeper Joe Hart, was visibly hampered by the injury in conceding Toni Kroos' opening goal.
Scans have now confirmed a fracture that appears certain to rule him out of the rest of the Premier League season, while also throwing his participation at the European Championship into major doubt.
A statement released by the Football Association on Sunday read: "Goalkeeper Jack Butland will miss Tuesday night's fixture against Netherlands at Wembley Stadium after fracturing his ankle.
"The Stoke City man sustained the injury in the first half of Saturday's 3-2 victory over Germany in Berlin and has now returned home.
"There will be no further call-ups to the squad at this moment in time."