Sale Sharks finally ended their European hoodoo with a bonus-point 29-20 victory over Pau in the European Rugby Challenge Cup on Saturday.
A 30-12 opening-round defeat at the Dragons made it eight straight defeats for Sale in Europe, dating back to a loss to Northampton Saints in the quarter-finals of the 2014 tournament.
However, tries from Brian Mujati, Mark Jennings, Sam James and Viliami Fihaki proved enough to earn a bonus-point victory at the AJ Bell Stadium on Saturday, the latter crossing with three minutes remaining.
Daniel Ramsay and Quentin Lespiaucq-Brettes scored in each half for Pau, who remained competitive throughout, but Sale were not to be denied.
The Dragons failed to build on their win over Sale, falling to an agonising 32-29 victory over Castres.
Castres - whose opening match with Pau was postponed due to last week's terror attacks in Paris - ran in four tries, with Daniel Kirkpatrick, Geoffrey Palis, Thomas Combezou and Alex Tulou touching down in a bonus-point win.
In Pool One, Connacht battled to a 21-17 victory over Brive to make it two wins from two, while Zebre defeated Worcester Warriors 27-8 to leave Pool Four wide open after two games.
The last match of the day saw Grenoble snatch a dramatic 27-20 victory over London Irish in the French Alps, courtesy of a last-gasp score from Clement Gelin.
Irish were 14-0 down after 11 minutes, but fought back impressively to pull level.
However, after 27 scoreless minutes, Gelin went over on the stroke of full-time, with Christophe Loustalot converting.