Lamine Diack has resigned as president of the International Athletics Foundation (IAF), the charitable arm of the IAAF, amid allegations of corruption.
The former IAAF president is under investigation by French prosecutors, who suspect the 82-year-old of receiving money to defer charges against Russian doping cheats.
Diack was provisionally suspended from his role as a honorary member of the International Olympic Committee (IOC) earlier on Tuesday, and has now tendered his resignation from the IAF.
An IAAF statement read: "The IAAF confirms it has tonight received a letter from Lamine Diack resigning his position as President of the International Athletics Foundation (IAF).
"This information has been passed to IAF Honorary President HSH Prince Albert II of Monaco. Discussions will be held in due course regarding the IAF and the appointment of a new IAF President."
The IAF helps promote athletics through various programmes and projects.
It was reported by the Sunday Times that Diack was paid EUR1million and the IAAF's former head of anti-doping Dr Gabriel Dolle EUR200,000 to cover up failed doping tests from Russian athletes.
Dr Dolle and Diack's son Papa Massata Diack were among four people who had charges brought against them from the IAAF's Ethics Commission for breaching its Code of Ethics.
Athletics has been engulfed in controversy, with an independent commission established by the World Anti-Doping Agency calling for the All-Russia Athletic Federation (ARAF) to be suspended by the IAAF on Monday.
The commission, which was led by former WADA chief Dick Pound, also raised concern within the IAAF.
The commission's report transmitted evidence of "corruption and bribery practices at the highest levels of international athletics" to Interpol for investigation.