It's the beginning of the end, as both Hillary Clinton and Donald Trump have cast their votes.
Heavily armed police joined Trump as he voted at Public School 59 in Manhattan, a short distance from Trump Tower. Hundreds of people watched from the street as Trump was greeted by a mixture of boos and cries of "Donald, Donald".
Trump arrived at the polling station with his wife Melania and daughter Ivanka, shortly after two topless female protesters had been removed from the building.
Speaking before he voted, Trump told Fox News: "I see so many dreams out there that didn't happen, that could have happened with leadership, proper leadership. People are hurt so badly."
Both candidates will be in New York on election night, with the Republican billing his planned event at a Hilton hotel as a "victory party".
Earlier Democratic candidate Clinton was joined by her husband Bill as she voted in Chappaqua, New York.
There was a heavy police presence in the city after US authorities received intelligence of a possible pre-election al Qaida attack, and more than 5,000 police officers have been assigned to secure central Manhattan.