Another hospital has been shelled in the Syrian city of Aleppo where further conflict between rebels and government forces has left at least 12 dead and at least 70 injured.
According to Syrian state TV dozens of people were killed or wounded when rebels fired rockets into the central government-held neighbourhood of Muhafaza.
Although the TV did not give a breakdown of the casualties, one of the rockets hit the Dubeet hospital, which a doctor from another clinic said killed four and injured more than 30.
The doctor said rebel bombardment of government-held parts of Aleppo on Tuesday killed a total of 12 people and wounded more than 70. The physician spoke on condition of anonymity for fear for his own safety.
Both sides shelled each other's neighbourhoods as the UN envoy for Syria was due to hold talks to try and restore a ceasefire that would include Aleppo, Syria's largest city, which has been the centre of violence in recent weeks but was not part of the latest partial truce.
In the past two weeks, more than 250 people have been killed in Aleppo during various conflicts which included another hospital being targeted.
The activist Britain-based Syrian Observatory for Human Rights confirmed the shelling of government-held parts of the city, and added seven were killed, including a child. The observatory said more than 50 were wounded, including some who were in critical condition, which could raise the death toll.
Also in northern Syria, war planes carried out intense air strikes on the city of Raqqa, the de facto capital of the extremist Islamic State group, in the early hours of Tuesday. Activist groups said it was not clear if the war planes were Russian or those of the US-led coalition.
The observatory, which has a network of activists around the country, said there were more than 35 air raids and 18 people were killed including five members of the Islamic State group. It said dozens were wounded.
The anti-IS group Raqqa Is Being Slaughtered Silently said the air strikes killed 10 and wounded dozens. The group said there were calls from mosque loudspeakers for the residents to donate blood.
IS suffered major setbacks over the past months in Syria against government forces and US-backed Kurdish fighters including the loss of the central historic city of Palmyra.