Prince Harry will ride out on a polo field for a fundraising match in aid of his Africa based charity Sentebale.
The event is a regular fixture for the organisation Harry founded in 2006 to help vulnerable children in the impoverished country of Lesotho.
Harry was in Lesotho this week attending the opening of Sentebale's Mamohato Children's Centre - a £2 million facility which will step-up the charity's work with young HIV sufferers.
Harry is expected to lead out the Sentebale team during the match being staged in South Africa, while Argentinian Nacho Figueras, a professional polo player, Ralph Lauren model and Sentebale ambassador, will captain the opposing team.
The event is being staged at the exclusive Val de Vie Estate - a leading polo, lifestyle and residential estate set in the Western Cape province.
Cathy Ferrier, Sentebale's chief executive, said: "Sentebale's annual polo fundraising event has gone from strength to strength over six consecutive years.
"We hope to raise even more money this year enabling us to care for and support many more children in Lesotho and across other southern African countries in the near future."
Among the guests reportedly invited are actress Laura Main, a star of the popular BBC series Call The Midwife, South African former Olympic gold medal winning swimmer Ryk Neethling, and British spoken word artist George the Poet, who performed at the opening ceremony of the Mamohato centre.