Celebrity Big Brother's Bit On The Side was taken off air 10 minutes early folowing an altercation between housemate Farrah Abraham and former contestant Aisleyne Horgan-Wallace.
Tensions flared early on when Horgan-Wallace gave a brutally frank assessment of American reality TV personality Abraham, dismissing her as a "horrible bitch".
The two stars, alongside 'Allo 'Allo actress Vicki Michelle, were panellists on the Celebrity Big Brother sister show presented by Rylan Clark, but it soon became clear there was no love lost between them.
The Sun reported Michelle was taken to hospital, having been injured by flying glass after champagne glasses and a chair were thrown.
The exchange began when Clark asked Horgan-Wallace: "Do you miss Farrah being in the house?"
"No I don't. She was just horrible," the former Big Brother 7 star responded. "She never took accountability for anything she did because she's a silly little girl.
"It's just pathetic. She's just nasty. There's one thing standing up for yourself and being a strong woman. There's another thing being a nasty horrible bitch. You've got your cheque, get on your plane and f*** off. No one likes you here."
Abraham hit back by slow-clapping Horgan-Wallace and saying: "Well done. Good job."
Later in the show, the 24-year-old American was asked her opinion of fellow Celebrity Big Brother housemate Austin Armacost. As she started to talk about his anger issues, Horgan-Wallace could be heard saying it was a shame Abraham did not work through her own issues. "Hag, be quiet!" Abraham said.
"Sorry?" Horgan-Wallace queried as Clark ordered everyone to "calm down".
The screen then flashed to the UK vs USA logo before Clark returned saying: "Hi guys, unfortunately, we did have to pop that up there due to a matter that happened, er, unfortunately we have lost our panel for the evening, but we are going to carry on."
The show ended 10 minutes earlier than scheduled with users on Twitter posting that a fight had broken out between Abraham and Horgan-Wallace which had left Michelle injured.
A Channel 5 spokesman said: "Celebrity Big Brother's Bit On The Side was interrupted this evening due to an incident on the set".
Celebrity Big Brother's Clark tweeted: "Apologies, we had to cut transmission due to reasons out of our control. Thanks to our loyal audience and viewers."